Weight loss and management is possible without frustrations
WHY WE PRESCRIBE ANTI-OBESITY MEDICATIONS?
Weight loss triggers an intricate array of neuroendocrine physiological adjustments, which intensify as weight loss progresses. Initially, they aim to decelerate and, in some cases, potentially cease weight loss. Over time, these adaptations may even contribute to weight regain.
understanding USe of medications for weight loss
WHO QUALIFIES FOR ANTI-OBESITY MEDICATIONS?
WHAT IS THE GOAL OF PRESCRIBING ANTI-OBESITY MEDICATIONS?
WHAT IS THE GOAL OF PRESCRIBING ANTI-OBESITY MEDICATIONS?
- Patients with comorbidities or those with a BMI of 27 or higher who qualify as obese may receive certain obesity medications.
- Comorbidities that may help determine qualification for obesity medicines include hypertension, diabetes mellitus, and sleep apnea.
- Some medications are unrestricted, however less effective.`
WHAT IS THE GOAL OF PRESCRIBING ANTI-OBESITY MEDICATIONS?
WHAT IS THE GOAL OF PRESCRIBING ANTI-OBESITY MEDICATIONS?
WHAT IS THE GOAL OF PRESCRIBING ANTI-OBESITY MEDICATIONS?
- Facilitate management of eating behavior.
- Facilitate weight loss and slow progression of weight gain/regain
- Improve the health, quality of life, and body weight of patients who are overweight or obese
- Counter physiologic adaptation
WHAT MEDICATIONS ARE AVAILABLE FOR WEIGHT LOSS?
Liraglutide Trade Name: Saxenda (2014)
Naltrexone/Bupropion Trade Name: Contrave (2014)
Liraglutide Trade Name: Saxenda (2014)
- GLP-1 receptor agonist
- Decreases gastric emptying and increases the sense of fullness
- Contraindications include pregnancy, personal or family history of medullary thyroid cancer, MEN type 2, pancreatitis, gallbladder disease, hypoglycemia, heart rate increase, renal impairment, Suicidal behavior
- Weight loss 5-10%
Semaglutide Trade Name: Wegovy (2021)
Naltrexone/Bupropion Trade Name: Contrave (2014)
Liraglutide Trade Name: Saxenda (2014)
- GLP-1 receptor agonist
- Decreases gastric emptying and increases the sense of fullness
- Contraindications include pregnancy, personal or FH or medullary thyroid cancer; MEN type 2, acute pancreatitis, acute gallbladder disease, hypoglycemia, increased heart rate, and renal impairment
- Weight loss up to 17.4%
Naltrexone/Bupropion Trade Name: Contrave (2014)
Naltrexone/Bupropion Trade Name: Contrave (2014)
Phenteramine/Topiramate ER Trade Name: Osymia (2012)
- Opioid agonist, decreases norepinephrine and dopamine uptake
- Exerts effect on appetite regulatory center and to regulate appetite and reduce c
- Contraindications include pregnancy, uncontrolled hypertension, seizure disorder, opioid use, anorexia or bulimia, suicidal behavior, hepatotoxicity, glaucoma
- Weight loss 5-10%
Phenteramine/Topiramate ER Trade Name: Osymia (2012)
Phenteramine/Topiramate ER Trade Name: Osymia (2012)
Phenteramine/Topiramate ER Trade Name: Osymia (2012)
- Stimulates sympathetic system
- Reduces appetite, decreases food consumption, and en
- May cause Fetal toxicity, increased heart rate, suicidal behavior, sleep disorder, cognitive impairment, hepatic impairment, and kidney stones
- Contraindications in pregnancy, glaucoma, hyperthyroidism, MAOI antidepressants
- Weight loss 5-10%
Orlistat Trade Name: Xenical or Alli (2007)
Phenteramine/Topiramate ER Trade Name: Osymia (2012)
Orlistat Trade Name: Xenical or Alli (2007)
- Decreases fat absorption
- Decreases absorption of fat-soluble vitamins
- Causes Diarrhea, fecal incontinence
- Contraindications include pregnancy, chronic malabsorption, and cholestasis.
- Weight loss 2-4%answers. Display the most frequently asked questions so everybody benefits.
Always contact our clinic before taking any any medications
HOW SHOULD ANTI-OBESITY MEDICATIONS BE USE?
- Medications may be an integral treatment modality for all patients who struggle with overweight or obesity
- There are off label medications that can be considered to treat obesity if FDA approved obesity medications are not affordable or approved by insurance
- Treatments likely will be required life-long commitment