
Semaglutide is a medication marketed under the name Wegovy and Ozempic. It is used for both type 2 diabetes management and weight loss in children and adults with obesity or overweight. It belongs to a class of drugs called GLP-1 receptor agonist, mimicking a naturally occurring hormone that regulates blood sugar and appetite.
How it works:
- Semaglutide stimulates insulin release from the pancreas, reducing blood sugar levels, especially after meals. It also helps the liver produce less sugar.
- It mimics the GLP-1 hormone, which helps the brain regulate appetite, leading to feelings of fullness and reducing hunger.
- By controlling blood sugar and suppressing appetite, semaglutide helps individuals achieve and maintain weight loss, particularly when combined with diet and exercise.
Key aspects of semaglutide:

- Administration: It can be administered as a weekly injection (e.g., Wegovy) or as an oral tablet (e.g., Rybelsus).
- Uses:
- Type 2 Diabetes: Primarily used to improve blood sugar control in individuals with type 2 diabetes.
- Weight Loss: Approved for chronic weight management in adults with obesity or overweight with at least one weight-related health condition.
- Benefits:
- Reduces blood sugar levels in type 2 diabetes.
- Can lead to significant weight loss.
- May reduce the risk of cardiovascular events in certain populations.
- Side Effects: Common side effects include nausea, vomiting, diarrhea, and constipation, which are often mild and may improve over time.
- Important Note: Semaglutide is a prescription medication and should be used under the guidance of a healthcare professional.