Semaglutide

Semaglutide is a medication marketed under the name Wegovy and Ozempic. It is used for both type 2 diabetes management and weight loss in children and adults with obesity or overweight.  It belongs to a class of drugs called GLP-1 receptor agonist, mimicking a naturally occurring hormone that regulates blood sugar and appetite. 

How it works:

  • Semaglutide stimulates insulin release from the pancreas, reducing blood sugar levels, especially after meals. It also helps the liver produce less sugar. 
  • It mimics the GLP-1 hormone, which helps the brain regulate appetite, leading to feelings of fullness and reducing hunger. 
  • By controlling blood sugar and suppressing appetite, semaglutide helps individuals achieve and maintain weight loss, particularly when combined with diet and exercise. 

Key aspects of semaglutide:

  • Administration: It can be administered as a weekly injection (e.g., Wegovy) or as an oral tablet (e.g., Rybelsus). 
  • Uses:
    • Type 2 Diabetes: Primarily used to improve blood sugar control in individuals with type 2 diabetes. 
    • Weight Loss: Approved for chronic weight management in adults with obesity or overweight with at least one weight-related health condition. 
  • Benefits:
    • Reduces blood sugar levels in type 2 diabetes. 
    • Can lead to significant weight loss. 
    • May reduce the risk of cardiovascular events in certain populations. 
  • Side Effects: Common side effects include nausea, vomiting, diarrhea, and constipation, which are often mild and may improve over time. 
  • Important Note: Semaglutide is a prescription medication and should be used under the guidance of a healthcare professional.